Chapter 20 Equine Alphaviruses

  1. Ferguson JA, Reeves WC, Hardy JL: Studies on immunity to alphaviruses in foals. Am J Vet Res 40:5–10, 1979. PUBMED Abstract
  2. Weaver SC, Bellew LA, Rico-Hesse R: Phylogenetic analysis of alphaviruses in the Venezuelan equine encephalitis complex and identification of the source of epizootic viruses. Virology 191:282–290, 1992. PUBMED Abstract
  3. Gibbs EPJ: Equine encephalitides caused by alphaviruses. In Coetzer JA, Tustin RC, editors: Infectious diseases of livestock, Oxford, 2004, Oxford University Press, pp 1014–1026.
  4. Griffin DE: Alphaviruses. In Knipe DM, Howley PM, editors: Fields virology, ed 5, Philidelphia, 2007, Wolters Kluwer Health/Lippincott Williams & Wilkins, pp 1023–1069.
  5. Powers AM, Roehrig JT: Alphaviruses. Methods Mol Biol 665:17–38, 2011. PUBMED Abstract
  6. Jacups SP, Whelan PI, Currie BJ: Ross River virus and Barmah Forest virus infections: a review of history, ecology, and predictive models, with implications for tropical northern Australia. Vector Borne Zoonotic Dis 8:283–297, 2008. PUBMED Abstract
  7. Weaver SC, Barrett AD: Transmission cycles, host range, evolution and emergence of arboviral disease. Nat Rev Microbiol 2:789–801, 2004. PUBMED Abstract
  8. Weaver SC: Host range, amplification and arboviral disease emergence. Arch Virol Suppl 19:33–44, 2005. PUBMED Abstract
  9. Gorelkin L: Venezuelan equine encephalomyelitis in an adult animal host. An electron microscopic study. Am J Pathol 73:425–442, 1973. PUBMED Abstract
  10. Pletnev SV, Zhang W, Mukhopadhyay S, et al: Locations of carbohydrate sites on alphavirus glycoproteins show that E1 forms an icosahedral scaffold. Cell 105:127–136, 2001. PUBMED Abstract
  11. Mukhopadhyay S, Chipman PR, Hong EM, et al: In vitro-assembled alphavirus core-like particles maintain a structure similar to that of nucleocapsid cores in mature virus. J Virol 76:11128–11132, 2002. PUBMED Abstract
  12. Zhang W, Mukhopadhyay S, Pletnev SV, et al: Placement of the structural proteins in Sindbis virus. J Virol 76:11645–11658, 2002. PUBMED Abstract
  13. Mukhopadhyay S, Zhang W, Gabler S, et al: Mapping the structure and function of the E1 and E2 glycoproteins in alphaviruses. Structure 14:63–73, 2006. PUBMED Abstract
  14. Wu SR, Haag L, Hammar L, et al: The dynamic envelope of a fusion class II virus. Prefusion stages of semliki forest virus revealed by electron cryomicroscopy. J Biol Chem 282:6752–6762, 2007. PUBMED Abstract
  15. Roehrig JT: Immunogens of encephalitis viruses. Vet Microbiol 37:273–284, 1993. PUBMED Abstract
  16. Strizki JM, Repik PM: Structural protein relationships among eastern equine encephalitis viruses. J Gen Virol 75 (Pt 11):2897–2909, 1994. PUBMED Abstract
  17. Brault AC, Powers AM, Holmes EC, et al: Positively charged amino acid substitutions in the e2 envelope glycoprotein are associated with the emergence of Venezuelan equine encephalitis virus. J Virol 76:1718–1730, 2002. PUBMED Abstract
  18. Calisher CH, Maness KS: Laboratory studies of Venezuelan equine encephalitis virus in equines, Texas, 1971. J Clin Microbiol 2:198–205, 1975. PUBMED Abstract
  19. Calisher CH, Emerson JK, Muth DJ, et al: Serodiagnosis of western equine encephalitis virus infections: relationships of antibody titer and test to observed onset of clinical illness. J Am Vet Med Assoc 183:438–440, 1983. PUBMED Abstract
  20. Calisher CH, Mahmud MI, el-Kafrawi AO, et al: Rapid and specific serodiagnosis of western equine encephalitis virus infection in horses. Am J Vet Res 47:1296–1299, 1986. PUBMED Abstract
  21. Hunt AR, Short WA, Johnson AJ, et al: Synthetic peptides of the E2 glycoprotein of Venezuelan equine encephalomyelitis virus. II. Antibody to the amino terminus protects animals by limiting viral replication. Virology 185:281–290, 1991. PUBMED Abstract
  22. Roehrig JT, Bolin RA: Monoclonal antibodies capable of distinguishing epizootic from enzootic varieties of subtype 1 Venezuelan equine encephalitis viruses in a rapid indirect immunofluorescence assay. J Clin Microbiol 35:1887–1890, 1997. PUBMED Abstract
  23. Thibodeaux BA, Liss NM, Panella AN, et al: Development of a human-murine chimeric immunoglobulin M for use in the serological detection of human alphavirus antibodies. Clin Vaccine Immunol 18:2181–2182, 2011. PUBMED Abstract
  24. Aaslestad HG, Hoffman EJ, Brown A: Fractionation of Eastern equine encephalitis virus by density gradient centrifugation in CsCl. J Virol 2:972–978, 1968. PUBMED Abstract
  25. Srihongse S, Grayson MA, Morris CD, et al: Eastern equine encephalomyelitis in upstate New York: studies of a 1976 epizootic by a modified serologic technique, hemagglutination reduction, for rapid detection of virus infections. Am J Trop Med Hyg 27:1240–1245, 1978. PUBMED Abstract
  26. Foster NM, Barber TL, Walton TE: Venezuelan equine encephalomyelitis virus: concentration, partial purification, inactivation and immunogenicity. Comp Immunol Microbiol Infect Dis 6:31–37, 1983. PUBMED Abstract
  27. Sudia WD, Newhouse VF, Beadle ID, et al: Epidemic Venezuelan equine encephalitis in North America in 1971: vector studies. Am J Epidemiol 101:17–35, 1975. PUBMED Abstract
  28. Monath TP, McLean RG, Cropp CB, et al: Diagnosis of eastern equine encephalomyelitis by immunofluorescent staining of brain tissue. Am J Vet Res 42:1418–1421, 1981. PUBMED Abstract
  29. Shope RE, Causey OR, De Andrade AH: The Venezuelan equine encephalomyelitis complex of group a arthropod-borne viruses, including Mucambo and Pixuna from the Amazon region of Brazil. Am J Trop Med Hyg 13:723–727, 1964. PUBMED Abstract
  30. Sekla LH, Stackiw W: Laboratory diagnosis of Western encephalomyelitis. Can J Public Health 67 Suppl 1:33–39, 1976. PUBMED Abstract
  31. Scott TW, Olson JG, All BP 3rd, et al: Detection of eastern equine encephalomyelitis virus antigen in equine brain tissue by enzyme-linked immunosorbent assay. Am J Vet Res 49:1716–1718, 1988. PUBMED Abstract
  32. Weaver SC, Hagenbaugh A, Bellew LA, et al: A comparison of the nucleotide sequences of eastern and western equine encephalomyelitis viruses with those of other alphaviruses and related RNA viruses. Virology 197:375–390, 1993. PUBMED Abstract
  33. Weaver SC, Powers AM, Brault AC, et al: Molecular epidemiological studies of veterinary arboviral encephalitides. Vet J 157:123–138, 1999. PUBMED Abstract
  34. Brault AC, Powers AM, Chavez CL, et al: Genetic and antigenic diversity among eastern equine encephalitis viruses from North, Central, and South America. Am J Trop Med Hyg 61:579–586, 1999. PUBMED Abstract
  35. Weaver SC, Scott TW, Rico-Hesse R: Molecular evolution of eastern equine encephalomyelitis virus in North America. Virology 182:774–784, 1991. PUBMED Abstract
  36. Weaver SC, Rico-Hesse R, Scott TW: Genetic diversity and slow rates of evolution in New World alphaviruses. Curr Top Microbiol Immunol 176:99–117, 1992. PUBMED Abstract
  37. Weaver SC, Hagenbaugh A, Bellew LA, et al: Genetic characterization of an antigenic subtype of eastern equine encephalomyelitis virus. Arch Virol 127:305–314, 1992. PUBMED Abstract
  38. Weaver SC, Bellew LA, Gousset L, et al: Diversity within natural populations of eastern equine encephalomyelitis virus. Virology 195:700–709, 1993. PUBMED Abstract
  39. Weaver SC, Hagenbaugh A, Bellew LA, et al: Evolution of alphaviruses in the eastern equine encephalomyelitis complex. J Virol 68:158–169, 1994. PUBMED Abstract
  40. Weaver SC, Hagenbaugh A, Bellew LA, et al: A comparison of the nucleotide sequences of eastern and western equine encephalomyelitis viruses with those of other alphaviruses and related RNA viruses. Virology 202:1083, 1994. PUBMED Abstract
  41. Bertram DS: Mosquitoes of British Honduras, with some comments on malaria, and on arbovirus antibodies in man and equines. Trans R Soc Trop Med Hyg 65:742–762, 1971. PUBMED Abstract
  42. Reisen WK, Lothrop HD, Presser SB, et al: Landscape ecology of arboviruses in southern California: temporal and spatial patterns of vector and virus activity in Coachella Valley, 1990-1992. J Med Entomol 32:255–266, 1995. PUBMED Abstract
  43. Reisen WK, Hardy JL, Chiles RE, et al: Ecology of mosquitoes and lack of arbovirus activity at Morro Bay, San Luis Obispo County, California. J Am Mosq Control Assoc 12:679–687, 1996. PUBMED Abstract
  44. Reisen WK, Lothrop HD, Presser SB, et al: Landscape ecology of arboviruses in southeastern California: temporal and spatial patterns of enzootic activity in Imperial Valley, 1991-1994. J Med Entomol 34:179–188, 1997. PUBMED Abstract
  45. Passler S, Pfeffer M: Detection of antibodies to alphaviruses and discrimination between antibodies to eastern and western equine encephalitis viruses in rabbit sera using a recombinant antigen and virus-specific monoclonal antibodies. J Vet Med B Infect Dis Vet Public Health 50:265–269, 2003. PUBMED Abstract
  46. Reisen WK, Martinez VM, Fang Y, et al: Role of California (Callipepla californica) and Gambel's (Callipepla gambelii) quail in the ecology of mosquito-borne encephalitis viruses in California, USA. Vector Borne Zoonotic Dis 6:248–260, 2006. PUBMED Abstract
  47. Brown CR, Strickler SA, Moore AT, et al: Winter ecology of Buggy Creek virus (Togaviridae, Alphavirus) in the Central Great Plains. Vector Borne Zoonotic Dis 10:355–363, 2010. PUBMED Abstract
  48. Weaver SC, Winegar R, Manger ID, et al: Alphaviruses: population genetics and determinants of emergence. Antiviral Res 94:242–257, 2012. PUBMED Abstract
  49. Morris CD, Srihongse S: An evaluation of the hypothesis of transovarial transmission of eastern equine encephalomyelitis virus by Culiseta melanura. Am J Trop Med Hyg 27:1246–1250, 1978. PUBMED Abstract
  50. Scott TW, Hildreth SW, Beaty BJ: The distribution and development of eastern equine encephalitis virus in its enzootic mosquito vector, Culiseta melanura. Am J Trop Med Hyg 33:300–310, 1984. PUBMED Abstract
  51. Weaver SC, Scott TW, Lorenz LH: Patterns of eastern equine encephalomyelitis virus infection in Culiseta melanura (Diptera: Culicidae). J Med Entomol 27:878–891, 1990. PUBMED Abstract
  52. Weaver SC, Scott TW, Lorenz LH, et al: Detection of eastern equine encephalomyelitis virus deposition in Culiseta melanura following ingestion of radiolabeled virus in blood meals. Am J Trop Med Hyg 44:250–259, 1991. PUBMED Abstract
  53. Molaei G, Oliver J, Andreadis TG, et al: Molecular identification of blood-meal sources in Culiseta melanura and Culiseta morsitans from an endemic focus of eastern equine encephalitis virus in New York. Am J Trop Med Hyg 75:1140–1147, 2006. PUBMED Abstract
  54. Chatterjee SN, Chakravarty MS, Chakravarty SK, et al: Serological survey for antibodies against chikungunya virus in Calcutta. Bull Calcutta Sch Trop Med 15:55–56, 1967. PUBMED Abstract
  55. Williams JE, Young OP, Watts DM, et al: Wild birds as eastern (EEE) and western (WEE) equine encephalitis sentinels. J Wildl Dis 7:188–194, 1971. PUBMED Abstract
  56. Morris CD, Caines AR, Woodall JP, et al: Eastern equine encephalomyelitis in upstate New York 1972-1974. Am J Trop Med Hyg 24:986–991, 1975. PUBMED Abstract
  57. McLean RG, Frier G, Parham GL, et al: Investigations of the vertebrate hosts of eastern equine encephalitis during an epizootic in Michigan, 1980. Am J Trop Med Hyg 34:1190–1202, 1985. PUBMED Abstract
  58. Hardy JL: The ecology of western equine encephalomyelitis virus in the Central Valley of California, 1945-1985. Am J Trop Med Hyg 37:18S–32S, 1987. PUBMED Abstract
  59. Reisen WK, Hardy JL, Presser SB: Evaluation of domestic pigeons as sentinels for detecting arbovirus activity in southern California. Am J Trop Med Hyg 46:69–79, 1992. PUBMED Abstract
  60. Howard JJ, Grayson MA, White DJ, et al: Evidence for multiple foci of eastern equine encephalitis virus (Togaviridae: Alphavirus) in central New York State. J Med Entomol 33:421–432, 1996. PUBMED Abstract
  61. Reisen WK, Lundstrom JO, Scott TW, et al: Patterns of avian seroprevalence to western equine encephalomyelitis and Saint Louis encephalitis viruses in California, USA. J Med Entomol 37:507–527, 2000. PUBMED Abstract
  62. Reisen WK, Kramer LD, Chiles RE, et al: Response of house finches to infection with sympatric and allopatric strains of western equine encephalomyelitis and St. Louis encephalitis viruses from California. J Med Entomol 37:259–264, 2000. PUBMED Abstract
  63. Reisen WK, Chiles RE, Kramer LD, et al: Method of infection does not alter response of chicks and house finches to western equine encephalomyelitis and St. Louis encephalitis viruses. J Med Entomol 37:250–258, 2000. PUBMED Abstract
  64. Reisen WK, Kramer LD, Chiles RE, et al: Encephalitis virus persistence in California birds: preliminary studies with house finches. J Med Entomol 38:393–399, 2001. PUBMED Abstract
  65. Reisen WK, Chiles RE, Martinez VM, et al: Encephalitis virus persistence in California birds: experimental infections in mourning doves (Zenaidura macroura). J Med Entomol 41:462–466, 2004. PUBMED Abstract
  66. Estep LK, McClure CJ, Burkett-Cadena ND, et al: A multi-year study of mosquito feeding patterns on avian hosts in a southeastern focus of eastern equine encephalitis virus. Am J Trop Med Hyg 84:718–726, 2011. PUBMED Abstract
  67. Oliveira A, Katholi CR, Burkett-Cadena N, et al: Temporal analysis of feeding patterns of Culex erraticus in central Alabama. Vector Borne Zoonotic Dis 11:413–421, 2011. PUBMED Abstract
  68. Burton AN, McLintock J, Rempel JG: Western equine encephalitis virus in Saskatchewan garter snakes and leopard frogs. Science 154:1029–1031, 1966. PUBMED Abstract
  69. Gebhardt LP, Jeor SC, Stanton GJ, et al: Ecology of Western encephalitis virus. Proc Soc Exp Biol Med 142:731–733, 1973. PUBMED Abstract
  70. Leung MK, McLintock J, Iversen J: Intranasal exposure of the Richardson's ground squirrel to Western equine encephalomyelitis virus. Can J Comp Med 42:184–191, 1978. PUBMED Abstract
  71. Main AJ: Virologic and serologic survey for eastern equine encephalomyelitis and certain other viruses in colonial bats of New England. J Wildl Dis 15:455–466, 1979. PUBMED Abstract
  72. Arrigo NC, Adams AP, Watts DM, et al: Cotton rats and house sparrows as hosts for North and South American strains of eastern equine encephalitis virus. Emerg Infect Dis 16:1373–1380, 2010. PUBMED Abstract
  73. Bedenice D, Bright A, Pedersen DD, et al: Humoral response to an equine encephalitis vaccine in healthy alpacas. J Am Vet Med Assoc 234:530–534, 2009. PUBMED Abstract
  74. Pursell AR, Mitchell FE, Seibold HR: Naturally occurring and experimentally induced eastern encephalomyelitis in calves. J Am Vet Med Assoc 169:1101–1103, 1976. PUBMED Abstract
  75. McGee ED, Littleton CH, Mapp JB, et al: Eastern equine encephalomyelitis in an adult cow. Vet Pathol 29:361–363, 1992. PUBMED Abstract
  76. Elvinger F, Liggett AD, Tang KN, et al: Eastern equine encephalomyelitis virus infection in swine. J Am Vet Med Assoc 205:1014–1016, 1994. PUBMED Abstract
  77. Elvinger F, Baldwin CA, Liggett AD, et al: Prevalence of exposure to eastern equine encephalomyelitis virus in domestic and feral swine in Georgia. J Vet Diagn Invest 8:481–484, 1996. PUBMED Abstract
  78. Veazey RS, Vice CC, Cho DY, et al: Pathology of eastern equine encephalitis in emus (Dromaius novaehollandiae). Vet Pathol 31:109–111, 1994. PUBMED Abstract
  79. Bauer RW, Gill MS, Poston RP, et al: Naurally occurring eastern equine encephalitis in a Hampshire wether. J Vet Diagn Invest 17:281–285, 2005. PUBMED Abstract
  80. Tate CM, Howerth EW, Stallknecht DE, et al: Eastern equine encephalitis in a free-ranging white-tailed deer (Odocoileus virginianus). J Wildl Dis 41:241–245, 2005. PUBMED Abstract
  81. Tully TN Jr, Shane SM, Poston RP, et al: Eastern equine encephalitis in a flock of emus (Dromaius novaehollandiae). Avian Dis 36:808–812, 1992. PUBMED Abstract
  82. Snoeyenbos GH, Weinack OM, Rosenau BJ: Immunization of pheasants for Eastern encephalitis. Avian Dis 22:386–390, 1978. PUBMED Abstract
  83. Faddou GP, Fellows GW: Clinical manifestations of eastern equine encephalitis in pheasants. Avian Dis 9:530–535, 1965. PUBMED Abstract
  84. Day JF, Stark LM: Eastern equine encephalitis transmission to emus (Dromaius novaehollandiae) in Volusia County, Florida: 1992 through 1994. J Am Mosq Control Assoc 12:429–436, 1996. PUBMED Abstract
  85. Kelen PT, Downs JA, Burkett-Cadena ND, et al: Habitat associations of eastern equine encephalitis transmission in Walton County Florida. J Med Entomol 49:746–756, 2012. PUBMED Abstract
  86. Lubelczyk C, Mutebi JP, Robinson S, et al: An epizootic of eastern equine encephalitis virus, Maine, USA in 2009: outbreak description and entomological studies. Am J Trop Med Hyg 88:95–102, 2013. PUBMED Abstract
  87. Moncayo AC, Edman JD, Finn JT: Application of geographic information technology in determining risk of eastern equine encephalomyelitis virus transmission. J Am Mosq Control Assoc 16:28–35, 2000. PUBMED Abstract
  88. Anonymous: West Nile virus disease and other arboviral diseases—United States, 2011. MMWR Morb Mortal Wkly Rep 61:510–514, 2012.
  89. Anonymous: Deaths from eastern equine encephalitis reported in the south. Am J Nurs 103:27, 2003.
  90. Anonymous: Eastern equine encephalitis—New Hampshire and Massachusetts, August-September 2005. MMWR Morb Mortal Wkly Rep 55:697–700, 2006.
  91. Anonymous: West Nile virus disease and other arboviral diseases—United States, 2010. MMWR Morb Mortal Wkly Rep 60:1009–1013, 2011.
  92. Silverman MA, Misasi J, Smole S, et al: Eastern equine encephalitis in children, Massachusetts and New Hampshire, USA, 1970-2010. Emerg Infect Dis 19:194–201, 2013. PUBMED Abstract
  93. Armstrong PM, Andreadis TG, Anderson JF, et al: Tracking eastern equine encephalitis virus perpetuation in the northeastern United States by phylogenetic analysis. Am J Trop Med Hyg 79:291–296, 2008. PUBMED Abstract
  94. Molaei G, Andreadis TG, Armstrong PM, et al: Vector-host interactions and epizootiology of eastern equine encephalitis virus in Massachusetts. Vector Borne Zoonotic Dis 13:312–323, 2013. PUBMED Abstract
  95. Weaver SC, Scott TW: Peritrophic membrane formation and cellular turnover in the midgut of Culiseta melanura (Diptera: Culicidae). J Med Entomol 27:864–873, 1990. PUBMED Abstract
  96. Young DS, Kramer LD, Maffei JG, et al: Molecular epidemiology of eastern equine encephalitis virus, New York. Emerg Infect Dis 14:454–460, 2008. PUBMED Abstract
  97. Ross WA, Kaneene JB: Evaluation of outbreaks of disease attributable to eastern equine encephalitis virus in horses. J Am Vet Med Assoc 208:1988–1997, 1996. PUBMED Abstract
  98. Schmitt SM, Cooley TM, Fitzgerald SD, et al: An outbreak of Eastern equine encephalitis virus in free-ranging white-tailed deer in Michigan. J Wildl Dis 43:635–644, 2007. PUBMED Abstract
  99. Howard JJ, Grayson MA, White DJ, et al: Evidence for multiple foci of eastern equine encephalitis virus (Togaviridae: Alphavirus) in central New York State. J Med Entomol 33:421–432, 1996. PUBMED Abstract
  100. Owen JC, Moore FR, Williams AJ, et al: Test of recrudescence hypothesis for overwintering of eastern equine encephalomyelitis virus in gray catbirds. J Med Entomol 48:896–903, 2011. PUBMED Abstract
  101. Walder R, Suarez OM: Studies of arboviruses in Southwestern Venezuela: I. Isolations of Venezuelan and eastern Equine Encephalitis viruses from sentinel hamsters in the Catatumbo region. Int J Epidemiol 5:375–378, 1976. PUBMED Abstract
  102. Walder R, Rosato RR, Eddy GA: Virion polypeptide heterogeneity among virulent and avirulent strains of eastern equine encephalitis (EEE) virus. Arch Virol 68:229–237, 1981. PUBMED Abstract
  103. Walder R, Suarez OM, Calisher CH: Arbovirus studies in the Guajira region of Venezuela: activities of eastern equine encephalitis and Venezuelan equine encephalitis viruses during an interepizootic period. Am J Trop Med Hyg 33:699–707, 1984. PUBMED Abstract
  104. Forshey BM, Guevara C, Laguna-Torres VA, et al: Arboviral etiologies of acute febrile illnesses in Western South America, 2000-2007. PLoS Negl Trop Dis 4:e787, 2010. PUBMED Abstract
  105. Turell MJ, O'Guinn ML, Dohm D, et al: Susceptibility of Peruvian mosquitoes to eastern equine encephalitis virus. J Med Entomol 45:720–725, 2008. PUBMED Abstract
  106. Aguilar PV, Robich RM, Turell MJ, et al: Endemic eastern equine encephalitis in the Amazon region of Peru. Am J Trop Med Hyg 76:293–298, 2007. PUBMED Abstract
  107. Silva ML, Galiza GJ, Dantas AF, et al: Outbreaks of Eastern equine encephalitis in northeastern Brazil. J Vet Diagn Invest 23:570–575, 2011. PUBMED Abstract
  108. Mendoza LP, Bronzoni RV, Takayanagui OM, et al: Viral infections of the central nervous system in Brazil. J Infect 54:589–596, 2007. PUBMED Abstract
  109. Figueiredo LT: Emergent arboviruses in Brazil. Rev Soc Bras Med Trop 40:224–229, 2007. PUBMED Abstract
  110. Bell JR, Hunkapiller MW, Hood LE, et al: Amino-terminal sequence analysis of the structural proteins of Sindbis virus. Proc Natl Acad Sci U S A 75:2722–2726, 1978. PUBMED Abstract
  111. Bell JR, Strauss EG, Strauss JH: Purification and amino acid compositions of the structural proteins of Sindbis virus. Virology 97:287–294, 1979. PUBMED Abstract
  112. Bell JR, Strauss JH: In vivo NH2-terminal acetylation of Sindbis virus proteins. J Biol Chem 256:8006–8011, 1981. PUBMED Abstract
  113. Bell JR, Rice CM, Hunkapiller MW, et al: The N-terminus of PE2 in Sindbis virus-infected cells. Virology 119:255–267, 1982. PUBMED Abstract
  114. Rice CM, Bell JR, Hunkapiller MW, et al: Isolation and characterization of the hydrophobic COOH-terminal domains of the Sindbis virion glycoproteins. J Mol Biol 154:355–378, 1982. PUBMED Abstract
  115. Arias C, Bell JR, Lenches EM, et al: Sequence analysis of two mutants of Sindbis virus defective in the intracellular transport of their glycoproteins. J Mol Biol 168:87–102, 1983. PUBMED Abstract
  116. Bell JR, Kinney RM, Trent DW, et al: An evolutionary tree relating eight alphaviruses, based on amino-terminal sequences of their glycoproteins. Proc Natl Acad Sci U S A 81:4702–4706, 1984. PUBMED Abstract
  117. Strauss EG, Rice CM, Strauss JH: Complete nucleotide sequence of the genomic RNA of Sindbis virus. Virology 133:92–110, 1984. PUBMED Abstract
  118. Strauss EG, Strauss JH: RNA viruses: genome structure and evolution. Curr Opin Genet Dev 1:485–493, 1991. PUBMED Abstract
  119. Ou JH, Rice CM, Dalgarno L, et al: Sequence studies of several alphavirus genomic RNAs in the region containing the start of the subgenomic RNA. Proc Natl Acad Sci U S A 79:5235–5239, 1982. PUBMED Abstract
  120. Rumenapf T, Strauss EG, Strauss JH: Subgenomic mRNA of Aura alphavirus is packaged into virions. J Virol 68:56–62, 1994. PUBMED Abstract
  121. Rumenapf T, Brown DT, Strauss EG, et al: Aura alphavirus subgenomic RNA is packaged into virions of two sizes. J Virol 69:1741–1746, 1995. PUBMED Abstract
  122. Strauss JH Jr, Burge BW, Pfefferkorn ER, et al: Identification of the membrane protein and “core” protein of Sindbis virus. Proc Natl Acad Sci U S A 59:533–537, 1968. PUBMED Abstract
  123. Ahlquist P, Strauss EG, Rice CM, et al: Sindbis virus proteins nsP1 and nsP2 contain homology to nonstructural proteins from several RNA plant viruses. J Virol 53:536–542, 1985. PUBMED Abstract
  124. Byrnes AP, Griffin DE: Binding of Sindbis virus to cell surface heparan sulfate. J Virol 72:7349–7356, 1998. PUBMED Abstract
  125. Gardner CL, Ebel GD, Ryman KD, et al: Heparan sulfate binding by natural eastern equine encephalitis viruses promotes neurovirulence. Proc Natl Acad Sci U S A 108:16026–16031, 2011. PUBMED Abstract
  126. Gardner CL, Burke CW, Tesfay MZ, et al: Eastern and Venezuelan equine encephalitis viruses differ in their ability to infect dendritic cells and macrophages: impact of altered cell tropism on pathogenesis. J Virol 82:10634–10646, 2008. PUBMED Abstract
  127. Gardner CL, Yin J, Burke CW, et al: Type I interferon induction is correlated with attenuation of a South American eastern equine encephalitis virus strain in mice. Virology 390:338–347, 2009. PUBMED Abstract
  128. Alsharifi M, Regner M, Blanden R, et al: Exhaustion of type I interferon response following an acute viral infection. J Immunol 177:3235–3241, 2006. PUBMED Abstract
  129. Shabman RS, Morrison TE, Moore C, et al: Differential induction of type I interferon responses in myeloid dendritic cells by mosquito and mammalian-cell-derived alphaviruses. J Virol 81:237–247, 2007. PUBMED Abstract
  130. Ryman KD, Klimstra WB: Host responses to alphavirus infection. Immunol Rev 225:27–45, 2008. PUBMED Abstract
  131. Morier L, Cantelar N, Soler M: Infection of a poikilothermic cell line (XL-2) with eastern equine encephalitis and western equine encephalitis viruses. J Med Virol 21:277–281, 1987. PUBMED Abstract
  132. Balasuriya UB, Heidner HW, Davis NL, et al: Alphavirus replicon particles expressing the two major envelope proteins of equine arteritis virus induce high level protection against challenge with virulent virus in vaccinated horses. Vaccine 20:1609–1617, 2002. PUBMED Abstract
  133. Fuscaldo AA, Aaslestad HG, Hoffman EJ: Biological, physical, and chemical properties of Eastern equine encephalitis virus. I. Purification and physical properties. J Virol 7:233–240, 1971. PUBMED Abstract
  134. Marker SC, Jahrling PB: Correlation between virus-cell receptor properties of alphaviruses in vitro and virulence in vivo. Arch Virol 62:53–62, 1979. PUBMED Abstract
  135. Liprandi F, Gómez B, Walder R: Replication of alphaviruses in cultures of donkey monocytes. Arch Virol 87:163–171, 1986. PUBMED Abstract
  136. Kim KH, Rümenapf T, Strauss EG, et al: Regulation of Semliki Forest virus RNA replication: a model for the control of alphavirus pathogenesis in invertebrate hosts. Virology 323:153–163, 2004. PUBMED Abstract
  137. Aguilar PV, Adams AP, Wang E, et al: Structural and nonstructural protein genome regions of eastern equine encephalitis virus are determinants of interferon sensitivity and murine virulence. J Virol 82:4920–4930, 2008. PUBMED Abstract
  138. Paessler S, Yun NE, Judy BM, et al: Alpha-beta T cells provide protection against lethal encephalitis in the murine model of VEEV infection. Virology 367:307–323, 2007. PUBMED Abstract
  139. Gibbs EP: Equine viral encephalitis. Equine Vet J 8:66–71, 1976. PUBMED Abstract
  140. Gibbs EPJ, Tsai TF: Eastern encephalitis. In Beran GW, Steele JH, editors: Handbook of zoonoses, ed 2, Boca Raton, FL, 1994, CRC Press.
  141. Scherer WF, Dickerman RW: Ecologic studies of Venezuelan encephalitis virus in southeastern Mexico. Correlations and conclusions. Am J Trop Med Hyg 21:86–89, 1972.
  142. Letson GW, Bailey RE, Pearson J, et al: Eastern equine encephalitis (EEE): a description of the 1989 outbreak, recent epidemiologic trends, and the association of rainfall with EEE occurrence. Am J Trop Med Hyg 49:677–685, 1993. PUBMED Abstract
  143. Wilson JH, Rubin HL, Lane TJ, et al: A survey of eastern equine encephalitis in Florida horses: prevalence, economic impact, and management practices, 1982-1983. Prev Vet Med 4:261–271, 2006.
  144. Miller LD, Pearson JE, Muhm RL: A comparison of clinical manifestations and pathology of the equine encephalitides: VEE, WEE, EEE. Proc Annu Meet U S Anim Health Assoc 629–631, 1973. PUBMED Abstract
  145. Meyer KF, Haring CM, Howitt B: The etiology of epizootic encephalomyelitis of horses in the San Joaquin Valley, 1930. Science 74:227–228, 1931. PUBMED Abstract
  146. Kissling RE, Chamberlain RW, Eidson ME, et al: Studies on the North American arthropod-borne encephalitides. II. Eastern equine encephalitis in horses. Am J Hyg 60:237–250, 1954. PUBMED Abstract
  147. Sahu SP, Alstad AD, Pedersen DD, et al: Diagnosis of eastern equine encephalomyelitis virus infection in horses by immunoglobulin M and G capture enzyme-linked immunosorbent assay. J Vet Diagn Invest 6:34–38, 1994. PUBMED Abstract
  148. Anonymous: Arbovirus encephalitis-diagnostic considerations. J Iowa Med Soc 66:333–334, 1976.
  149. Gregory CR, Latimer KS, Niagro FD, et al: Detection of eastern equine encephalomyelitis virus RNA in formalin-fixed, paraffin-embedded tissues using DNA in situ hybridization. J Vet Diagn Invest 8:151–155, 1996. PUBMED Abstract
  150. Patterson JS, Maes RK, Mullaney TP, et al: Immunohistochemical diagnosis of eastern equine encephalomyelitis. J Vet Diagn Invest 8:156–160, 1996. PUBMED Abstract
  151. Linssen B, Kinney RM, Aguilar P, et al: Development of reverse transcription-PCR assays specific for detection of equine encephalitis viruses. J Clin Microbiol 38:1527–1535, 2000. PUBMED Abstract
  152. Brown TM, Mitchell CJ, Nasci RS, et al: Detection of eastern equine encephalitis virus in infected mosquitoes using a monoclonal antibody-based antigen-capture enzyme-linked immunosorbent assay. Am J Trop Med Hyg 65:208–213, 2001. PUBMED Abstract
  153. Franklin RP, Kinde H, Jay MT, et al: Eastern equine encephalomyelitis virus infection in a horse from California. Emerg Infect Dis 8:283–288, 2002. PUBMED Abstract
  154. Studdert MJ, Azuolas JK, Vasey JR, et al: Polymerase chain reaction tests for the identification of Ross River, Kunjin and Murray Valley encephalitis virus infections in horses. Aust Vet J 81:76–80, 2003. PUBMED Abstract
  155. Wang E, Paessler S, Aguilar PV, et al: Reverse transcription-PCR-enzyme-linked immunosorbent assay for rapid detection and differentiation of alphavirus infections. J Clin Microbiol 44:4000–4008, 2006. PUBMED Abstract
  156. Bastian FO, Wende RD, Singer DB, et al: Eastern equine encephalomyelitis. Histopathologic and ultrastructural changes with isolation of the virus in a human case. Am J Clin Pathol 64:10–13, 1975. PUBMED Abstract
  157. Weaver SC, Lorenz LH, Scott TW: Pathologic changes in the midgut of Culex tarsalis following infection with Western equine encephalomyelitis virus. Am J Trop Med Hyg 47:691–701, 1992. PUBMED Abstract
  158. Brown TP, Roberts W, Page RK: Acute hemorrhagic enterocolitis in ratites: isolation of eastern equine encephalomyelitis virus and reproduction of the disease in ostriches and turkey poults. Avian Dis 37:602–605, 1993. PUBMED Abstract
  159. Poonacha KB, Gregory CR, Vickers ML: Intestinal lesions in a horse associated with eastern equine encephalomyelitis virus infection. Vet Pathol 35:535–538, 1998. PUBMED Abstract
  160. Del Piero F, Wilkins PA, Dubovi EJ, et al: Clinical, pathologic, immunohistochemical, and virologic findings of eastern equine encephalomyelitis in two horses. Vet Pathol 38:451–456, 2001. PUBMED Abstract
  161. Hunt AR, Frederickson S, Hinkel C, et al: A humanized murine monoclonal antibody protects mice either before or after challenge with virulent Venezuelan equine encephalomyelitis virus. J Gen Virol 87:2467–2476, 2006. PUBMED Abstract
  162. Lukaszewski RA, Brooks TJ: Pegylated alpha interferon is an effective treatment for virulent venezuelan equine encephalitis virus and has profound effects on the host immune response to infection. J Virol 74:5006–5015, 2000. PUBMED Abstract
  163. Chikkanna-Gowda CP, McNally S, Sheahan BJ, et al: Inhibition of murine K-BALB and CT26 tumour growth using a Semliki Forest virus vector with enhanced expression of IL-18. Oncol Rep 16:713–719, 2006. PUBMED Abstract
  164. Julander JG, Siddharthan V, Blatt LM, et al: Effect of exogenous interferon and an interferon inducer on western equine encephalitis virus disease in a hamster model. Virology 360:454–460, 2007. PUBMED Abstract
  165. Wu JQ, Barabé ND, Huang YM, et al: Pre- and post-exposure protection against Western equine encephalitis virus after single inoculation with adenovirus vector expressing interferon alpha. Virology 369:206–213, 2007. PUBMED Abstract
  166. Sentsui H, Wu D, Murakami K, et al: Antiviral effect of recombinant equine interferon-gamma on several equine viruses. Vet Immunol Immunopathol 135:93–99, 2010. PUBMED Abstract
  167. Jochim MM, Barber TL: Immune response of horses after simultaneous or sequential vaccination against eastern, western, and Venezuelan equine encephalomyelitis. J Am Vet Med Assoc 165:621–625, 1974. PUBMED Abstract
  168. Barber TL, Walton TE, Lewis KJ: Efficacy of trivalent inactivated encephalomyelitis virus vaccine in horses. Am J Vet Res 39:621–625, 1978. PUBMED Abstract
  169. Koloff WJ: Insecticide spray. Arch Intern Med 129:834, 1972. PUBMED Abstract
  170. Omohundro RE: Venezuelan equine encephalomyelitis emergency operation. J Am Vet Med Assoc 161:1516–1518, 1972. PUBMED Abstract
  171. Saulmon EE: Use of multiagency coordination in dealing with epizootics of zoonoses. J Am Vet Med Assoc 161:1520–1523, 1972. PUBMED Abstract
  172. Uryvaev LV, Lebedev AIU, Sokolova TM, et al: [Capsid glycoprotein of E2 encephalitis virus, western equine: primary structure of gene and its product]. Dokl Akad Nauk 357:134–139, 1997. PUBMED Abstract
  173. Netolitzky DJ, Schmaltz FL, Parker MD, et al: Complete genomic RNA sequence of western equine encephalitis virus and expression of the structural genes. J Gen Virol 81:151–159, 2000. PUBMED Abstract
  174. Hahn CS, Lustig S, Strauss EG, et al: Western equine encephalitis virus is a recombinant virus. Proc Natl Acad Sci U S A 85:5997–6001, 1988. PUBMED Abstract
  175. Weaver SC, Kang W, Shirako Y, et al: Recombinational history and molecular evolution of western equine encephalomyelitis complex alphaviruses. J Virol 71:613–623, 1997. PUBMED Abstract
  176. Cilnis MJ, Kang W, Weaver SC: Genetic conservation of Highlands J viruses. Virology 218:343–351, 1996. PUBMED Abstract
  177. Bell JR, Bond MW, Hunkapiller MW, et al: Structural proteins of Western equine encephalitis virus: amino acid compositions and N-terminal sequences. J Virol 45:708–714, 1983. PUBMED Abstract
  178. Powers AM, Brault AC, Shirako Y, et al: Evolutionary relationships and systematics of the alphaviruses. J Virol 75:10118–10131, 2001. PUBMED Abstract
  179. Sabattini MS, Monath TP, Mitchell CJ, et al: Arbovirus investigations in Argentina, 1977-1980. I. Historical aspects and description of study sites. Am J Trop Med Hyg 34:937–944, 1985. PUBMED Abstract
  180. Monath TP, Sabattini MS, Pauli R, et al: Arbovirus investigations in Argentina, 1977-1980. IV. Serologic surveys and sentinel equine program. Am J Trop Med Hyg 34:966–975, 1985. PUBMED Abstract
  181. Mitchell CJ, Darsie RF Jr, Monath TP, et al: The use of an animal-baited net trap for collecting mosquitoes during western equine encephalitis investigations in Argentina. J Am Mosq Control Assoc 1:43–47, 1985. PUBMED Abstract
  182. Hoff GL, Bigler WJ, Buff EE, et al: Occurrence and distribution of western equine encephalomyelitis in Florida. J Am Vet Med Assoc 172:351–352, 1978. PUBMED Abstract
  183. Karabatsos N, Lewis AL, Calisher CH, et al: Identification of Highlands J virus from a Florida horse. Am J Trop Med Hyg 39:603–606, 1988. PUBMED Abstract
  184. Iversen JO: Western Equine encephalitis. In Beran GW, Steele JH, editors: Handbook of zoonoses, ed 2, Boca Raton, FL, 1994, CRC Press.
  185. Hildreth SW, Beaty BJ: Detection of eastern equine encephalomyelitis virus and Highlands J virus antigens within mosquito pools by enzyme immunoassay (EIA). I. A laboratory study. Am J Trop Med Hyg 33:965–972, 1984. PUBMED Abstract
  186. Andreadis TG, Anderson JF, Tirrell-Peck SJ: Multiple isolations of eastern equine encephalitis and highlands J viruses from mosquitoes (Diptera: Culicidae) during a 1996 epizootic in southeastern Connecticut. J Med Entomol 35:296–302, 1998. PUBMED Abstract
  187. Calisher CH, Monath TP, Muth DJ, et al: Characterization of Fort Morgan virus, an alphavirus of the western equine encephalitis virus complex in an unusual ecosystem. Am J Trop Med Hyg 29:1428–1440, 1980. PUBMED Abstract
  188. Agafonov VI, Gol'din RB, Lev MI, et al: [Detection of the degree of infection of mosquitos in the Far East with group A arboviruses antigenically close to the Semliki forest virus.] Voen Med Zh 52–54, 1974. PUBMED Abstract
  189. Wagstaff KH, Dickson SL, Bailey A: Western equine encephalitis surveillance in Utah. J Am Mosq Control Assoc 2:201–203, 1986. PUBMED Abstract
  190. Janousek TE, Kramer WL: Surveillance for arthropod-borne viral activity in Nebraska, 1994-1995. J Med Entomol 35:758–762, 1998. PUBMED Abstract
  191. Reisen WK, Meyer RP, Presser SB, et al: Effect of temperature on the transmission of western equine encephalomyelitis and St. Louis encephalitis viruses by Culex tarsalis (Diptera: Culicidae). J Med Entomol 30:151–160, 1993. PUBMED Abstract
  192. Walton WE, Schreiber ET, Mulla MS: Distribution of Culex tarsalis larvae in a freshwater marsh in Orange County, California. J Am Mosq Control Assoc 6:539–543, 1990. PUBMED Abstract
  193. Walton WE, Tietze NS, Mulla MS: Ecology of Culex tarsalis (Diptera: Culicidae): factors influencing larval abundance in mesocosms in southern California. J Med Entomol 27:57–67, 1990. PUBMED Abstract
  194. Day JF, Stark LM, Zhang JT, et al: Antibodies to arthropod-borne encephalitis viruses in small mammals from southern Florida. J Wildl Dis 32:431–436, 1996. PUBMED Abstract
  195. Dunbar MR, Cunningham MW, Roof JC: Seroprevalence of selected disease agents from free-ranging black bears in Florida. J Wildl Dis 34:612–619, 1998. PUBMED Abstract
  196. Bianchi TI, Avilés G, Sabattini MS: Biological characteristics of an enzootic subtype of western equine encephalomyelitis virus from Argentina. Acta Virol 41:13–20, 1997. PUBMED Abstract
  197. Aviles G, Bianchi TI, Daffner JF, et al: [Post-epizootic activity of Western equine encephalitis virus in Argentina.] Rev Argent Microbiol 25:88–99, 1993. PUBMED Abstract
  198. Thomas LA, Eklund CM, Rush WA: Susceptibility of garter snakes (Thamnophis spp.) to western equine encephalomyelitis virus. Proc Soc Exp Biol Med 99:698–700, 1958. PUBMED Abstract
  199. Thomas LA, Eklund CM: Overwintering of western equine encephalomyelitis virus in experimentally infected garter snakes and transmission to mosquitoes. Proc Soc Exp Biol Med 105:52–55, 1960. PUBMED Abstract
  200. Thomas LA, Eklund CM: Overwintering of western equine encephalomyelitis virus in garter snakes experimentally infected by Culex tarsalis. Proc Soc Exp Biol Med 109:421–424, 1962. PUBMED Abstract
  201. Gebhardt LP, Stanton GJ, Hill DW, et al: Natural overwintering hosts of the virus of western equine encephalitis. N Engl J Med 271:172–177, 1964. PUBMED Abstract
  202. Spalatin J, Connell R, Burton AN, et al: Western equine encephalitis in Saskatchewan reptiles and amphibians, 1961-1963. Can J Comp Med Vet Sci 28:131–142, 1964. PUBMED Abstract
  203. Bast TF, Whitney E, Benach JL: Considerations on the ecology of several arboviruses in eastern Long Island. Am J Trop Med Hyg 22:109–115, 1973. PUBMED Abstract
  204. Thomas LA, Patzer ER, Cory JC, et al: Antibody development in garter snakes (Thamnophis spp.) experimentally infected with western equine encephalitis virus. Am J Trop Med Hyg 29:112–117, 1980. PUBMED Abstract
  205. Reisen WK, Presser SB, Lin J, et al: Viremia and serological responses in adult chickens infected with western equine encephalomyelitis and St. Louis encephalitis viruses. J Am Mosq Control Assoc 10:549–555, 1994. PUBMED Abstract
  206. Deleted in proof.
  207. Huyvaert KP, Moore AT, Panella NA, et al: Experimental inoculation of house sparrows (Passer domesticus) with buggy creek virus. J Wildl Dis 44:331–340, 2008. PUBMED Abstract
  208. Deleted in proof.
  209. Deleted in proof.
  210. Leung MK, Burton A, Iversoen J: Natural infections of Richardson's ground squirrels with western equine encephalomyelitis virus, Saskatchewan, Canada, 1964-1973. Can J Microbiol 21:954–958, 1975. PUBMED Abstract
  211. Leung MK, Iversen J, McLintock J, et al: Subcutaneous exposure of the Richardson's ground squirrel (Spermophilus richardsonii Sabine) to western equine encephalomyelitis virus. J Wildl Dis 12:237–246, 1976. PUBMED Abstract
  212. Hardy JL, Reeves WC, Rush WA, et al: Experimental infection with western equine encephalomyelitis virus in wild rodents indigenous to Kern County, California. Infect Immun 10:553–564, 1974. PUBMED Abstract
  213. Hardy JL, Presser SB, Chiles RE, et al: Mouse and baby chicken virulence of enzootic strains of western equine encephalomyelitis virus from California. Am J Trop Med Hyg 57:240–244, 1997. PUBMED Abstract
  214. Logue CH, Bosio CF, Welte T, et al: Virulence variation among isolates of western equine encephalitis virus in an outbred mouse model. J Gen Virol 90:1848–1858, 2009. PUBMED Abstract
  215. Reed DS, Larsen T, Sullivan LJ, et al: Aerosol exposure to western equine encephalitis virus causes fever and encephalitis in cynomolgus macaques. J Infect Dis 192:1173–1182, 2005. PUBMED Abstract
  216. Zlotnik I, Peacock S, Grant DP, et al: The pathogenesis of western equine encephalitis virus (W.E.E.) in adult hamsters with special reference to the long and short term effects on the C.N.S. of the attenuated clone 15 variant. Br J Exp Pathol 53:59–77, 1972. PUBMED Abstract
  217. Castorena KM, Peltier DC, Peng W, et al: Maturation-dependent responses of human neuronal cells to western equine encephalitis virus infection and type I interferons. Virology 372:208–220, 2008. PUBMED Abstract
  218. Peltier DC, Lazear HM, Farmer JR, et al: Neurotropic arboviruses induce interferon regulatory factor 3-mediated neuronal responses that are cytoprotective, interferon independent, and inhibited by Western equine encephalitis virus capsid. J Virol 87:1821–1833, 2013. PUBMED Abstract
  219. Lillie LE, Wong FC, Drysdale RA: Equine epizootic of western encephalomyelitis in Manitoba—1975. Can J Public Health 67 Suppl 1:21–27, 1976. PUBMED Abstract
  220. Meyer KF, Wood F, Haring CM, et al: Susceptibility of nonimmune, hyperimmunized horses and goats to Eastern, Western and Argentine virus of equine encephalomyelitis. Proc Soc Exp Biol Med 32:56–58, 1934.
  221. Julander JG, Smee DF, Morrey JD, et al: Effect of T-705 treatment on western equine encephalitis in a mouse model. Antiviral Res 82:169–171, 2009. PUBMED Abstract
  222. Sindac JA, Yestrepsky BD, Barraza SJ, et al: Novel inhibitors of neurotropic alphavirus replication that improve host survival in a mouse model of acute viral encephalitis. J Med Chem 55:3535–3545, 2012. PUBMED Abstract
  223. Kinney RM, Tsuchiya KR, Sneider JM, et al: Genetic evidence that epizootic Venezuelan equine encephalitis (VEE) viruses may have evolved from enzootic VEE subtype I-D virus. Virology 191:569–580, 1992. PUBMED Abstract
  224. Weaver SC, Salas R, Rico-Hesse R, et al: Re-emergence of epidemic Venezuelan equine encephalomyelitis in South America. VEE Study Group. Lancet 348:436–440, 1996. PUBMED Abstract
  225. Calisher CH, Sasso DR, Sather GE: Possible evidence for interference with Venezuelan equine encephalitis virus vaccination of equines by pre-existing antibody to Eastern or Western Equine encephalitis virus, or both. Appl Microbiol 26:485–488, 1973. PUBMED Abstract
  226. Young NA: Origin of epidemics of Venezuelan equine encephalitis. J Infect Dis 125:565–567, 1972. PUBMED Abstract
  227. Lord RD: History and geographic distribution of Venezuelan equine encephalitis. Bull Pan Am Health Organ 8:100–110, 1974. PUBMED Abstract
  228. Zehmer RB, Dean PB, Sudia WD, et al: Venezuelan equine encephalitis epidemic in Texas, 1971. Health Serv Rep 89:278–282, 1974. PUBMED Abstract
  229. Calisher CH, Maness KC: Virulence of Venezuelan equine encephalomyelitis virus subtypes for various laboratory hosts. Appl Microbiol 28:881–884, 1974. PUBMED Abstract
  230. Weaver SC, Pfeffer M, Marriott K, et al: Genetic evidence for the origins of Venezuelan equine encephalitis virus subtype IAB outbreaks. Am J Trop Med Hyg 60:441–448, 1999. PUBMED Abstract
  231. Mackenzie RM, de Siger J, Parra D: Venezuelan equine encephalitis virus: comparison of infectivity and virulence of strains V-38 and P676 in donkeys. Am J Trop Med Hyg 25:494–499, 1976. PUBMED Abstract
  232. Steele KE, Davis KJ, Stephan K, et al: Comparative neurovirulence and tissue tropism of wild-type and attenuated strains of Venezuelan equine encephalitis virus administered by aerosol in C3H/HeN and BALB/c mice. Vet Pathol 35:386–397, 1998. PUBMED Abstract
  233. Oberste MS, Weaver SC, Watts DM, et al: Identification and genetic analysis of Panama-genotype Venezuelan equine encephalitis virus subtype ID in Peru. Am J Trop Med Hyg 58:41–46, 1998. PUBMED Abstract
  234. Oberste MS, Fraire M, Navarro R, et al: Association of Venezuelan equine encephalitis virus subtype IE with two equine epizootics in Mexico. Am J Trop Med Hyg 59:100–107, 1998. PUBMED Abstract
  235. Oberste MS, Schmura SM, Weaver SC, et al: Geographic distribution of Venezuelan equine encephalitis virus subtype IE genotypes in Central America and Mexico. Am J Trop Med Hyg 60:630–634, 1999. PUBMED Abstract
  236. Rico-Hesse R, Weaver SC, de Siger J, et al: Emergence of a new epidemic/epizootic Venezuelan equine encephalitis virus in South America. Proc Natl Acad Sci U S A 92:5278–5281, 1995. PUBMED Abstract
  237. Estrada-Franco JG, Navarro-Lopez R, Freier JE, et al: Venezuelan equine encephalitis virus, southern Mexico. Emerg Infect Dis 10:2113–2121, 2004. PUBMED Abstract
  238. Weaver SC, Anishchenko M, Bowen R, et al: Genetic determinants of Venezuelan equine encephalitis emergence. Arch Virol Suppl (18):43–64, 2004. PUBMED Abstract
  239. Fernandez Z, Moncayo AC, Carrara AS, et al: Vector competence of rural and urban strains of Aedes (Stegomyia) albopictus (Diptera: Culicidae) from Sao Paulo State, Brazil for IC, ID, and IF subtypes of Venezuelan equine encephalitis virus. J Med Entomol 40:522–527, 2003. PUBMED Abstract
  240. Brault AC, Powers AM, Ortiz D, et al: Venezuelan equine encephalitis emergence: enhanced vector infection from a single amino acid substitution in the envelope glycoprotein. Proc Natl Acad Sci U S A 101:11344–11349, 2004. PUBMED Abstract
  241. Greene IP, Paessler S, Austgen L, et al: Envelope glycoprotein mutations mediate equine amplification and virulence of epizootic Venezuelan equine encephalitis virus. J Virol 79:9128–9133, 2005. PUBMED Abstract
  242. Smith DR, Carrara AS, Aguilar PV, et al: Evaluation of methods to assess transmission potential of Venezuelan equine encephalitis virus by mosquitoes and estimation of mosquito saliva titers. Am J Trop Med Hyg 73:33–39, 2005. PUBMED Abstract
  243. Walder R, Suarez OM, Calisher CH: Arbovirus studies in southwestern Venezuela during 1973-1981. II. Isolations and further studies of Venezuelan and eastern equine encephalitis, Una, Itaqui, and Moju viruses. Am J Trop Med Hyg 33:483–491, 1984. PUBMED Abstract
  244. Calisher CH, Kinney RM, de Souza Lopes O, et al: Identification of a new Venezuelan equine encephalitis virus from Brazil. Am J Trop Med Hyg 31:1260–1272, 1982. PUBMED Abstract
  245. Dietz WH Jr, Alvarez O Jr, Martin DH, et al: Enzootic and epizootic Venezuelan equine encephalomyelitis virus in horses infected by peripheral and intrathecal routes. J Infect Dis 137:227–237, 1978. PUBMED Abstract
  246. Johnson KM, Martin DH: Venezuelan equine encephalitis. Adv Vet Sci Comp Med 18:79–116, 1974. PUBMED Abstract
  247. Walton TE, Alvarez O Jr, Buckwalter RM, et al: Experimental infection of horses with enzootic and epizootic strains of Venezuelan equine encephalomyelitis virus. J Infect Dis 128:271–282, 1973. PUBMED Abstract
  248. Sudia WD, Newhouse VF: Epidemic Venezuelan equine encephalitis in North America: a summary of virus-vector-host relationships. Am J Epidemiol 101:1–13, 1975. PUBMED Abstract
  249. Sudia WD, Fernandez L, Newhouse VF, et al: Arbovirus vector ecology studies in Mexico during the 1972 Venezuelan equine encephalitis outbreak. Am J Epidemiol 101:51–58, 1975. PUBMED Abstract
  250. Sudia WD, McLean RG, Newhouse VF, et al: Epidemic Venezuelan equine encephalitis in North America in 1971: vertebrate field studies. Am J Epidemiol 101:36–50, 1975. PUBMED Abstract
  251. Barrera R, Ferro C, Navarro JC, et al: Contrasting sylvatic foci of Venezuelan equine encephalitis virus in northern South America. Am J Trop Med Hyg 67:324–334, 2002. PUBMED Abstract
  252. Barrera R, Torres N, Freier JE, et al: Characterization of enzootic foci of Venezuelan equine encephalitis virus in western Venezuela. Vector Borne Zoonotic Dis 1:219–230, 2001. PUBMED Abstract
  253. Young NA, Johnson KM, Gauld LW: Viruses of the Venezuelan equine encephalomyelitis complex. Experimental infection of Panamanian rodents. Am J Trop Med Hyg 18:290–296, 1969. PUBMED Abstract
  254. Young NA, Johnson KM: Viruses of the Venezuelan equine encephalomyelitis complex. Infection and cross-challenge of rodents with VEE, Mucambo, and Pixuna viruses. Am J Trop Med Hyg 18:280–289, 1969. PUBMED Abstract
  255. Carrara AS, Coffey LL, Aguilar PV, et al: Venezuelan equine encephalitis virus infection of cotton rats. Emerg Infect Dis 13:1158–1165, 2007. PUBMED Abstract
  256. Carrara AS, Gonzales G, Ferro C, et al: Venezuelan equine encephalitis virus infection of spiny rats. Emerg Infect Dis 11:663–669, 2005. PUBMED Abstract
  257. Smith DR, Carrara AS, Aguilar PV, et al: Evaluation of methods to assess transmission potential of Venezuelan equine encephalitis virus by mosquitoes and estimation of mosquito saliva titers. Am J Trop Med Hyg 73:33–39, 2005. PUBMED Abstract
  258. Scherer WF, Ordonez JV, Jahrling PB, et al: Observations of equines, humans and domestic and wild vertebrates during the 1969 equine epizootic and epidemic of Venezuelan encephalitis in Guatemala. Am J Epidemiol 95:255–266, 1972. PUBMED Abstract
  259. Scherer WF, Campillo-Sainz C, de Mucha-Macías J, et al: Ecologic studies of Venezuelan encephalitis virus in southeastern Mexico. VII. Infection of man. Am J Trop Med Hyg 21:79–85, 1972. PUBMED Abstract
  260. Scherer WF, Dickerman RW: Ecologic studies of Venezuelan encephalitis virus in southeastern Mexico. 8. Correlations and conclusions. Am J Trop Med Hyg 21:86–89, 1972. PUBMED Abstract
  261. Chamberlain RW, Kissling RE, Stamm DD, et al: Transmission of eastern equine encephalitis to horses by Aedes sollicitans mosquitoes. Am J Trop Med Hyg 5:802–808, 1956. PUBMED Abstract
  262. Weaver SC, Ferro C, Barrera R, et al: Venezuelan equine encephalitis. Annu Rev Entomol 49:141–174, 2004. PUBMED Abstract
  263. Nichols JB, Lassing EB, Bigler WJ, et al: An evaluation of military sentry dogs as a sentinel system to everglades virus (Venezuelan equine encephalitis Fe3-7C strain). Mil Med 140:710–712, 1975. PUBMED Abstract
  264. Dickerman RW, Scherer WF, Navarro E, et al: The involvement of dogs in endemic cycles of Venezuelan encephalitis virus. Am J Epidemiol 98:311–314, 1973. PUBMED Abstract
  265. Dickerman RW, Baker GJ, Ordonez JV, et al: Venezuelan equine encephalomyelitis viremia and antibody responses of pigs and cattle. Am J Vet Res 34:357–361, 1973. PUBMED Abstract
  266. Scherer WF, Anderson K, Pancake BA, et al: Search for epizootic-like Venezuelan encephalitis virus at enzootic habitats in Guatemala during 1969-1971. Am J Epidemiol 103:576–588, 1976. PUBMED Abstract
  267. Bowen GS, McLean RG: Experimental infection of birds with epidemic Venezuelan encephalitis virus. Am J Trop Med Hyg 26:808–814, 1977. PUBMED Abstract
  268. Weaver SC, Scherer WF, Taylor CA, et al: Laboratory vector competence of Culex (Melanoconion) cedecei for sympatric and allopatric Venezuelan equine encephalomyelitis viruses. Am J Trop Med Hyg 35:619–623, 1986. PUBMED Abstract
  269. Turell MJ: Vector competence of three Venezuelan mosquitoes (Diptera: Culicidae) for an epizootic IC strain of Venezuelan equine encephalitis virus. J Med Entomol 36:407–409, 1999. PUBMED Abstract
  270. Turell MJ, Barth J, Coleman RE: Potential for Central American mosquitoes to transmit epizootic and enzootic strains of Venezuelan equine encephalitis virus. J Am Mosq Control Assoc 15:295–298, 1999. PUBMED Abstract
  271. Turell MJ, Dohm DJ, Fernandez R, et al: Vector competence of Peruvian mosquitoes (Diptera: Culicidae) for a subtype IIIC virus in the Venezuelan equine encephalomyelitis complex isolated from mosquitoes captured in Peru. J Am Mosq Control Assoc 22:70–75, 2006. PUBMED Abstract
  272. Mitchell CJ, Monath TP, Sabattini MS, et al: Host-feeding patterns of Argentine mosquitoes (Diptera: Culicidae) collected during and after an epizootic of western equine encephalitis. J Med Entomol 24:260–267, 1987. PUBMED Abstract
  273. Mitchell CJ, Monath TP, Sabattini MS, et al: Arbovirus investigations in Argentina, 1977-1980. II. Arthropod collections and virus isolations from Argentine mosquitoes. Am J Trop Med Hyg 34:945–955, 1985. PUBMED Abstract
  274. Mendez W, Liria J, Navarro JC, et al: Spatial dispersion of adult mosquitoes (Diptera: Culicidae) in a sylvatic focus of Venezuelan equine encephalitis virus. J Med Entomol 38:813–821, 2001. PUBMED Abstract
  275. Linthicum KJ, Logan TM, Bailey CL, et al: Venezuelan equine encephalomyelitis virus infection in and transmission by the tick Amblyomma cajennense (Arachnida: Ixodidae). J Med Entomol 28:405–409, 1991. PUBMED Abstract
  276. Linthicum KJ, Dickson DL, Logan TM: Feeding efficiency of larval Hyalomma truncatum (Acari: Ixodidae) on hosts previously exposed to ticks. J Med Entomol 29:310–313, 1992. PUBMED Abstract
  277. Linthicum KJ, Logan TM: Laboratory transmission of Venezuelan equine encephalomyelitis virus by the tick Hyalomma truncatum. Trans R Soc Trop Med Hyg 88:126, 1994. PUBMED Abstract
  278. Spotts DR, Reich RM, Kalkhan MA, et al: Resistance to alpha/beta interferons correlates with the epizootic and virulence potential of Venezuelan equine encephalitis viruses and is determined by the 5′ noncoding region and glycoproteins. J Virol 72:10286–10291, 1998. PUBMED Abstract
  279. Schoneboom BA, Fultz MJ, Miller TH, et al: Astrocytes as targets for Venezuelan equine encephalitis virus infection. J Neurovirol 5:342–354, 1999. PUBMED Abstract
  280. Schoneboom BA, Lee JS, Grieder FB: Early expression of IFN-alpha/beta and iNOS in the brains of Venezuelan equine encephalitis virus-infected mice. J Interferon Cytokine Res 20:205–215, 2000. PUBMED Abstract
  281. Schoneboom BA, Catlin KM, Marty AM, et al: Inflammation is a component of neurodegeneration in response to Venezuelan equine encephalitis virus infection in mice. J Neuroimmunol 109:132–146, 2000. PUBMED Abstract
  282. Steele KE, Seth P, Catlin-Lebaron KM, et al: Tunicamycin enhances neuroinvasion and encephalitis in mice infected with Venezuelan equine encephalitis virus. Vet Pathol 43:904–913, 2006. PUBMED Abstract
  283. Walton TE, Luedke AJ, Jochim MM, et al: Duration of immunity of horses vaccinated with strain TC-83 Venezuelan equine encephalomyelitis virus vaccine. Proc Annu Meet U S Anim Health Assoc (77):196–202, 1973. PUBMED Abstract
  284. Venezuelan equine encephalomyelitis. In Monath TP, editor: The arboviruses: epidemiology and ecology, Boca Raton, 1989, CRC Press, pp 203–231.
  285. Parker RL, Dean PB, Zehmer RB: Public health aspects of Venezuelan equine encephalitis. J Am Vet Med Assoc 162:777–778, 1973. PUBMED Abstract
  286. Walton TE, Alvarez O Jr, Buckwalter RM, et al: Experimental infection of horses with an attenuated Venezuelan equine encephalomyelitis vaccine (strain TC-83). Infect Immun 5:750–756, 1972. PUBMED Abstract
  287. Walton TE, Johnson KM: Epizootiology of Venezuelan equine encephalomyelitis in the Americas. J Am Vet Med Assoc 161:1509–1515, 1972. PUBMED Abstract
  288. Walton TE, Johnson KM: Persistence of neutralizing antibody in Equidae vaccinated with Venezuelan equine encephalomyelitis vaccine strain TC-83. J Am Vet Med Assoc 161:916–918, 1972. PUBMED Abstract